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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25eb3b53f00323b1e978625de4760c3ef4749f67ca86b501f7dd85b15e9b690d' 
  AND token = 'y7mEAlkM9Uz5yyybf2ALixNlEfQlGrqXhvh77xK0MY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}