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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7cfb4ce49f129da7916ce4e0db424a63de65c3de9c26bd4c849398b5df85c0' 
  AND token = 'QIF6NhHg1a/XuRbQ72i1kB/rP5CuoNQAKeZRKlD/QKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}