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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72acfb608a4e24e4050dd3234ef6132e26aa72c1120c2ae9a66d879f8482453f' 
  AND token = 'l0THs4z/OqSGHJemCdoBsVkV0excA9Rq9/0g8w72fDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}