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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3255aa231bb81ed12c6b11923dc3ac75f8636289cbe8f3b29212a4bc330da568' 
  AND token = 'xEbL1gF4p3jqUV5y+o79uKBR4JkU6EHRd85S3OgX/WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}