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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bc19fa4891fa7bbc420e33ecaddb9251a7236de88ef2f81d6f709bbfee5e52' 
  AND token = 'csZ6FOtI4Rt6u+j5rXcDnu2Wbe2636GvsLBxWPuma3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}