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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee028bdb767076f2ac396c801c17f46c76a767bf4b1bcf2446f7b6a945b4b46' 
  AND token = 'NisHT0CPOKqzAL99tqY8f/36ayKp4KFuIsZ1Q+Y/geI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}