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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3081f2f53808bf5fa44aa3a9f1044a1ead1f6009a883d3164847756bf9297007' 
  AND token = 'JB9rnJB9XByyHviWT7zm2XMPcfuzx2O6Kbu4o1K5Q/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}