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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372335b9e8ed22c31a64242a13693da1c2716ccc081bc4c69a46d35cc794de99' 
  AND token = '2Or9pEFuJ+PJC58GnNKvSniJMd3koaISheTrf14WQ5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}