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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145752cc122d1482849f940da284f5174941819c923ef737d680d10f850ebad1' 
  AND token = 'fAQWZtnax7ukJrsnYglLvgjivUANJzg5v9OpJKn471E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}