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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34c0b54515a8c49b0116d06b86339a2ccfa145a60d4e797ed94d6277f449e196' 
  AND token = 'XR1d/0/2UwcmXdJEK9jBmlJFWPNtILNXXMdDRXYlhI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}