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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946ac0f45ce616601b92c6267db0036d13933861447e2c57aac71c7cabae02de' 
  AND token = 'pZ3BTOAecS2xLcbrhT9zWv+U9cXiaLCWrtNRBisMN6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}