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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223fa2113e07e0c566c3f916ddc918f9f86b8ba43ac937663d6aeb5880208959' 
  AND token = 'FTPNExPkf4xNWSdGNXF+nuL49VXOxzMY4Gk9FlN2XEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}