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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2165834aed4f3e9f8143f9ebfa56808f3c03234e8a0a6f9c9a2a64debcc1cb' 
  AND token = 'dQr7gLMYiToAAifnr7v/eStCjkSx+ep3bleu2F0OFGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}