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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79d225bea676603347067dc0476783bd737b8b21e074dca521afc32cb6f68814' 
  AND token = '6Nqwwi6NLaQhw6es7iYyXolgqdVjksmQNd0zz0hxe0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}