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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ea5bbfab8c27b268f9cb91e72fd60635597cad5878b92b7f163f52e4ac5826' 
  AND token = 'TSErHjkKpXIkIoyHwgq9FJvjLKs3g+i8MeHp3ikfIbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}