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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a804c0dfcc0383bda48e0b9f876a6161272603bfe519a0c64028cc76b03573a' 
  AND token = '8EFx0Z3avhY/y6LIsmZvyMiXpy56fwnH9BkkTBvSp0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}