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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9e520bf4afa203849744a172175da11e5b570766fe56ccc306f87f86b6493e' 
  AND token = 'SF17d1qS+wJ/HZQnEz6+65dQRtlmgfoU2DsJTdH1eLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}