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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6959b5d7f3aeec9861937ae8f94ea7a5f45ff3955f7cb48c0dbcdfff94f3f761' 
  AND token = 'ZiAdxRY1RnmfEivCBMLEbuQYfPfhtkQ1vF6je52LbUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}