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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe005ff38b114cfce8e40c51b18615f75172d687ae18e4f3012573789acf01f3' 
  AND token = 'auDVezUfvWf0br71qcY184WX336CvLU4EBwtFQCNyNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}