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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14dd77a6199c01b1ab15afb7639d3aa8a4af55f80a0f2766b3d1d4decc398824' 
  AND token = '9mdBu0DD6KsqNYH7BhKnfXPogcrCYbigT2EyUNMoYlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}