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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b86872d2b366b20a20f311974957543e087bb043c306ad978c47ea934dae5c2' 
  AND token = 'O3pmcIIz2MlMnZuKq4hmzI9OQX7LjGB0R/XDrq5X8H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}