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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a5a02e8f146882903f1fa9edeac287d1a526f6809d3a31d75f2958b4f997f2' 
  AND token = 'z1ptu8iOjyJ7dXxCVnYTJd22fHnrWcDEGEbdekoH9uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}