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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b08ed3822d2c317112c531624843468f4112f1c0eb8db5402531d77a6707644' 
  AND token = 'VfP6E/61rGbkRVMxhaHySTItfiVK/MXsmbib/Wu2Grs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}