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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a933b4fb62b4ca41d13bd0525b54ccf29152e8c4ee39c407770ddc9b30071740' 
  AND token = 'SFW0jqY7SgxnBwtAFVNkzJq7MTnjzTaIdTjX8GsC+yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}