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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3389be923aee36ee335fb536b1a1f7685b0321d9b4d4b37057b6cef4b91bfd' 
  AND token = 'gArW0jlkwN+BNzidKuf4DoCm7HbZLphbu2lbfcN+P1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}