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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0d44ecc98592f2a77fb74c1bb0b05685b89503ef17ca9c1bcffaee42c08a0f' 
  AND token = '9W7zOVBSFQaZq27yi+z8CEd/dkE+9gORgA6UM5MM/FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}