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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6316099ba0647c82be6a73a0c6a6f097b7d3680e835dc2f22fb00a751e7ce8e3' 
  AND token = 'Wk9D+UqIRPZbbl9V+gOsk4ICw6hNcyZ9aL8+VlJBqGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}