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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c79eab6fc303b41c24bc01c0f9717338a5027fd917f1b1ec501b5fada88376' 
  AND token = 'rql5x4GhqzM3djXDwA2oH//jg64Xp42JDF43pD8A2a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}