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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394b1318f6d5332e046e7a85603fc9352819d6fdfd3de67d9426e96bf5c5f4d2' 
  AND token = 'fmF/vIT3IoFfMIwR0LT6ddLIhrrWYOBbP6Xbj4H44uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}