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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff7350f55f0bf7b29b90273bfc95475dda089cc017d25f6767b6e1a5d01d713' 
  AND token = 'QLDDoGzTBA/XzvvXbC236Bz5r+o9IFwhUFyTwgTAX2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}