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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d12011913e2b166d40c6eb1771c3c54e2da834c123d02067b306eb1a2138425' 
  AND token = 'BgCW1iMj2d24MY/7PhQC14qxoG4sUd+rzDgWIUnd9WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}