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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e099c7f0416a6716e115dee03b0f1341002aae8428f2da1a18d833c6d585c027' 
  AND token = '3bxHVEaWiUiOzQmuT0yYUf6J/zKJQTFJVsP5Y3hNm+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}