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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd922d6a087acbf6859c4a72ca273c5726a5fc2fb0bf63d6cd19c7291da8dea72' 
  AND token = 'qL9yJVmHFI6SZBzT85OvANlLtgDN6wNRyxKfXoPBoFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}