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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d93d41cb8bdd3b0986c1e040c4cfffe71ced807fd692aaa69d27c4f85851a0' 
  AND token = 'NKy9N1xBf5WUyJaUr9TK4zqMzcNbGWod/kvwi/O+8to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}