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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5fb0eb0b7f70cf0c778c10d5e036938386e0437e0883b3cf397b90591980a4' 
  AND token = 'Fnx5WXxbvAn3O6m01u2kdzo94LAPCTf2yszJ9EtLezQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}