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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acb46f3594647901dd7678718e9ff5d479d89821d4ec03066e437f5b635d2e3' 
  AND token = 'jHDxUO24GQJ32AB/6f1ioAldXCHbDd/Z6NRhOOnm7ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}