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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc7ae7c1a75c45c7b88f3c4a84ec87ca2ad36e386904551be88fbbde9a756b49' 
  AND token = 'W9WbjxYKp4gESGTYFJh/owmgUgzbxtFAEGAD4kRM2pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}