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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0890ed04d56755c2a5fe03f3df704ccd75d4a5769948282d84d5f195172f05cf' 
  AND token = 'kYSvG6VZ1KA0dtftSs+hpsz31sImqSEUfNhAC1rVdQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}