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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead18a64228a8c72bf21d7b7bafa1b1aec01b930b39b3b897d35695a89c6468d' 
  AND token = 'T5B0ROkMaDhtscWUVdirle3epqHf3V9ouo2dY3fqO+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}