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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfe38e458a43ed165340eb9ed415f3ec0a4cd324a877e5e49cee8be1fa574501' 
  AND token = '++MAQJfh9Ix1+7wRvelCatrL2ocrQ4gOHDkkAHOjFPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}