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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e5d2829278c0a7049745789e1e89244619d9b782e40a3ff98baa83a89bf1df' 
  AND token = 'vn1b4PIY763jyG/Hy49YebTruwp+Ho/kySHHxcCpBSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}