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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef899d301125c949e5dc393db73f99dbfb5d1141998bcf6a4ffeea8833a28d8a' 
  AND token = 'yG+BgAYiTctw4Sp6pB0oWzFZoXp3ew6JX24T0okjSP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}