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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46922f1fcf495c22e9b125d536df63150e94c93f40246eddee7a5c98c444d421' 
  AND token = 'se2PqXCDsB0uyencQe9GPf9sBx8ssVa07xNMXxwn0Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}