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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9e6aece0cc979ea3a09ca0767109bfa59d2a33769fa529d99308cb1e1b652b' 
  AND token = 'F/ntgAC9mxcJ1LBpUvOE6zU1g3evaGfQxkpu2Ycscgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}