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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ca436d162f3c8f14e9876a1c3a51050083ae7b9d81dc84b35e35073a5b09da' 
  AND token = 'iv6DFcN6YaNHyo7k/beBoA7M6FXn2z07fD0Ihh6tD80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}