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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856dc1a9440d6b7d2382a8bd3546e24fe7690368bd7260075e332fa13e9c45a4' 
  AND token = 'AaYvlR0ewy1cYOAgmxl1L0XWvd6XeGLF+KmdwnfeiYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}