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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6321874fed82b93a140b88f4ecb666c694f0f97f9791fcf9f54599ccc8e9a44d' 
  AND token = '2TNTEO0SEAsp334BQN9RQfon86GkPCBcPFlzSj1S6dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}