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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e10f6c4365c836280bc9ddf760d5ddf656b5fbfa55fbbe193d8c0153e412ed' 
  AND token = 'vPMrWKhh/4t9N1U9SV1hqoB6voAWqjVapch9XQj0OH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}