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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb33680adf6a7640fc943b9bfa7cec7ca42ea05d39c2a2591befa2dbc3ea534' 
  AND token = 'LrolhOtJIC5dUDPX37I42sZNtjs9j5CJBw/3pZp8/YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}