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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af09b80053f7c34c186447697b5b238c9b4c49bb41c6fef5e1ef3ea8193a9701' 
  AND token = 'SwQxhQOapaLE3Bx+mfYQsbqh16LCczY1sa0HPKgpuxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}